Rui Yin (3283)

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The Role of SUMO Modification on Protein Mislocalization in Cancer

Hometown:Guangzhou, China

Department: Biology

Advisor: Oliver Kerscher


One hallmark of cancer is the altered protein localization within transformed cells. I hypothesize that SUMO, a small protein tag, plays a critical role in this mislocalization, and I will identify SUMO-modified proteins that are differentially localized within these cells. This is relevant because the role of sumoylation in protein localization may lead to the discovery of new disease markers.


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