Mark Pownall (3283)

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The Role of Ploidy in Embryonic Plasticity

Hometown: Powhatan, Virginia

Department: Biology

Advisor: Margaret Saha

Research in our lab has shown that Xenopus laevis embryos undergo a profound recovery following an experimental genetic disturbance. We hypothesize that the presence of multiple genome copies (known as polyploidy) may enhance the compensatory ability of embryos. I will test this hypothesis using other Xenopus species with different ploidy levels and examine how gene expression is regulated in polyploid cells, a condition that frequently occurs in cancer and cellular pathogenesis in humans.

All William & Mary Honors Fellowships fundraising supports the Charles Center Honors Fellowships Fund. Direct support for individual undergraduate research projects is distributed by the Roy R. Charles Center for Academic Excellence


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