Lindsay Chatkewitz

By William & Mary

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Developing A Novel Selenocysteine Tool Towards Treating Neurodegenerative Disorders

Alzheimer’s and general cognitive decline have been shown to be inhibited by selenocysteine, a highly reactive amino acid. However, its protective role is not well understood and studies are complicated by its reactive nature. As such, I will be developing a light activated selenocysteine, that will allow researchers to control the reactive nature of this amino acid. Moreover, this photo-sensitive selenocysteine will be incorporated into proteins to expand its utility. This novel tool will allow myself and other researchers to expand our studies on the protective role of selenocysteine in neurodegenerative disorders. 

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