Anna Tram Do (3283)

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Hydrogen-Deuterium Exchange and Fragmentation Studies of Peptides Containing Lysine, Serine and Cysteine Homologs

Hometown: Falls Church, Virginia

Department: Chemistry

Advisor: John Poutsma 

Mass spectrometry-based proteomic studies rely on automated peptide sequencing algorithms. These algorithms depend on empirically-derived rules, and the presence of modified amino acids or selective cleavages can prevent identification of the peptides. Understanding the mechanisms of peptide fragmentation will refine these rules for improved peptide identification. My honors thesis will investigate structure and intramolecular bonding of the peptides in the gas-phase.

All William & Mary Honors Fellowships fundraising supports the Charles Center Honors Fellowships Fund. Direct support for individual undergraduate research projects is distributed by the Roy R. Charles Center for Academic Excellence

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Matthew B. Zimmt
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Monica Do
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Tuan Do
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