Michael Salomon (3283)

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Investigating Cancer Causing Mutations

Hometown: Midlothian, Virginia

Department: Biology

Advisor: Lizabeth Allison

Description: My Honors Thesis investigates how the disruption of protein trafficking into and out the cell nucleus contributes to cancer. I am characterizing the effects of mutant thyroid hormone receptor rc6-TRalpha1 I116R, A225T, M388I. This mutant thyroid hormone receptor was isolated from renal clear cell carcinoma, the most common type of kidney cancer. My project explores how these mutations disrupt the nuclear trafficking of mutant and wild type thyroid hormone receptors and contribute to cancer.

All William & Mary Honors Fellowships fundraising supports the Charles Center Honors Fellowships Fund. Direct support for individual undergraduate research projects is distributed by the Roy R. Charles Center for Academic Excellence

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James C Green
Ken Salomon
Mark W. Borghesani
Gregory J Giardiello
Elizabeth Armstrong
Neal W Salomon
Susan Salomon
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